Dupixent Dupilumab Eczema Treatments


Eczema is a broad term which refers to a group of skin conditions that can affect all age groups. Generally, eczema is a chronic (long-lasting) inflammatory condition causing dry, red patches of skin which can often be very itchy. Severity can be mild to severe with eczema affecting large or small parts of the skin. Commonly, it is found on the flexors (areas like the bends behind the elbows or the back of the knees).

Atopic eczema (also known as atopic dermatitis) is the most common type of eczema. It is most commonly found in children, although it can develop in adults as well. The skin may become red and cracked, and its severity may differ. There may be periods of time where the eczema is less noticeable, and other times where it is particularly severe. The term “atopic” means that this form of eczema results from a genetic tendency to develop an allergic reaction.

Dupixent as a Treatment 

One treatment available for atopic eczema is Dupixent. Developed by Regeneron, this FDA-approved medication is an injection indicated for use in adult patients who have moderate-to-severe atopic eczema and who have little to no success with other treatments, such as topical creams. According to Dupixent’s website (please click here to visit), the success rate with the medicine is quite remarkable. In clinical studies with over 2,100 patients, over 1 in 3 reportedly saw clear or almost clear skin in 16 weeks, while over half saw significant skin improvement.

People with atopic dermatitis have immune systems which produce more skin inflammation than normal. This results in red, itchy patches. Dupixent works by controlling this immune system response. The main ingredient in Dupixent is dupilumab, which blocks certain biological responses in the body that cause the skin inflammation.

Typically, patients get injected with two 300 mg doses of Dupixent initially, followed by 300 mg every two weeks.

Side effects of Dupixent can include hypersensitivity and conjunctivitis (an eye disorder). To read more about these side effects and others, please click here. Talk to your doctor to discuss current medical conditions and conflicting medication before taking Dupixent.

Featured image: Depositphotos / Tharakorn

Posted on May 5, 2023